The Simultaneous Human FVIII/vWF Purification and Virus Inactivation Combined in Chromatographic Column

نویسندگان

  • Sergiy P Havryliuk
  • Ievgenia M Krasnobryzha
  • Olena S Havryliuk
  • Georgii L Volkov
چکیده

Abbreviations: FVIII/vWF: Complex of Factor VIII and von Willebrand Factor; MW: Molecular Weight; NDF: Number of Degree of Freedom; S/D: Solvent/Detergent; LEV/LEVs: Virus (es) Enveloped by Lipid Membrane; NLEV/NLEVs: Non-enveloped Virus (es); IFA method: Method of Immune-fermental Analysis; FITC: Fluorescein Isothiocyanate; RT-PCR method: Real-time PCR Method; TCID50: 50% Tissue Culture Infectious Dose; DBC: Dynamic Binding Capacity; T-DBC: Temperature-depending Binding Capacity; SEC: Size Exclusion Chromatography; IEC: Ion Exchange Chromatography; RPC: Reverse Phase Chromatography; HPLC: High Performance Liquid Chromatography; GC: Gas Chromatography; FID detector: Flame Ionization Detector; UV-detector: Ultra Violet Detector

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تاریخ انتشار 2017